The 9p21 Locus and Coronary Heart Disease: Initiator, Promoter, or Precipitator?⁎
Coronary heart disease (CHD), a major cause of worldwide morbidity/mortality (), is a multifactorial, multistage disorder to which both environmental and genetic factors contribute () (). Despite methodologic advances, including genomewide association studies, progress in elucidating CHD genetics has been slow, and the number and impact of well-validated associations remain few and modest. One of [...]